Z. Gordon Jiang, MD, PhD

Dr. Jiang is a transplant hepatologist and physician-scientist with a research interest in steatotic liver disease.  Dr. Jiang received MD and Ph.D. from Boston University School of Medicine. Dr. Jiang is an assistant professor at Harvard Medical School. He is an associate director of the physician-scientist track at BIDMC Internal Medicine. He co-directs the Systemic Manifestation of Metabolic Disease Research Hub at BIDMC and BIDMC Translational Biorepository and Databank. He is the founder of the Preclinical Liver Research Center at BIDMC sponsored by Massachusetts Life Science Center. 

As a physician, Dr. Jiang runs a fatty liver clinic and takes care of patients before and after liver transplant. Dr. Jiang is the principal investigator of an NIH-funded laboratory focusing on studying how lipid metabolism is altered in hepatocytes (liver cells), which contributes to the progression of alcohol-associated liver disease (ALD) and metabolic dysfunction associated steatotic liver diseases (MASLD), especially in the setting of liver fibrosis and liver failure. He has pioneered the use of NMR profiling and VLDL-lipidomics to understand liver cell dysfunction and has identified lipoprotein Z, an abnormal lipoprotein whose presence strongly prognosticates outcomes in alcohol-related hepatitis. Dr. Jiang’s research focuses on identifying key genes and pathways regulating lipid metabolism in human liver cells and developing novel strategies to harness liver cell fate through RNA-based therapeutics.