Study: Infant Vaccine Biorepository
Nickname: IVB
In this study, infants from all over the US contribute to science by providing a home-collected (tiny) blood sample.
180 enrolled to date
Funding: BIDMC Hub Spark Grant, Massachusetts Consortium for Pathogen Readiness (MassCPR), Harvard University William F. Milton Fund
Study: Immune profiling in healthy and complicated pregnancies
Nickname: Treg
Pregnant participants donate blood samples and placenta cord blood, human milk and other samples throughout pregnancy and postpartum to study the immune system changes in pregnancy.
184/300 enrolled to date (12/10/25)
Funding: NIH/NICHD, Burroughs Wellcome Fund, American Association of Obstetricians and Gynecologists Foundation (AAOGF), OBGYN Philanthropic support
Study: COVID-19 and other Respiratory Pathogen Biorepository
Nickname: COVID-19 Biorepository
Comment: Pregnant, lactating, and non-pregnant participants contribute blood and other optional samples to better understand diagnosis, treatment, and prevention of COVID-19, influenza, respiratory syncytial virus (RSV), and other respiratory pathogens
Graphic: 1107 enrolled total/409 pregnant or lactating
Funding: NIH/NIAID, Massachusetts Consortium for Pathogen Readiness (MassCPR), Harvard University William F. Milton Fund
Study: First trimester uterine decidua biorepository
Nickname: CVS study
Pregnant participants undergoing a chorionic villus sampling procedure donate left-over tissue from the procedure to study the early uterine immune changes in pregnancy that might predict preeclampsia
124 enrolled to date (12/10/25)
Funding: NIH/NICHD, Burroughs Wellcome Fund, American Association of Obstetricians and Gynecologists Foundation (AAOGF), OBGYN Dept Philanthropic support
Study: Understanding Motivations for Participating in Vaccine Clinical Research
Nickname: Clinical Trial Motivations
Comment: Pregnant and non-pregnant participants in our previous observational and interventional trials answer an anonymous survey for us to better understand participant motivations for participating in research
229 enrolled total
46 pregnant or lactating
18 with medical immunosuppression
Funding: OBGYN Philanthropic support
Study: (No longer enrolling) Evidence-based cesarean for patients with obesity undergoing cesarean delivery NCT03651076
Nickname: Traxi study
Comment: Randomized clinical trial to study surgical outcomes, patient reported and provider-reported outcomes with use of traxi device
No longer enrolling; stay tuned for final study publication
Funding: none, device donation by Laborie