Equipment and Technologies

We’re Committed to Continuously Evolving Our Technology and Service Portfolio

Agilent 2100 Bioanalyzer: The Agilent Bioanalyzer is an established automated electrophoresis tool for the sample quality control of biomolecules. It provides highly precise analytical evaluation of RNA and DNA samples for objective assessment of sizing, quantitation, integrity and purity from RNA input, cDNA synthesis, as well as sequencing library quality and sizing using minimal sample volume.

Formulatrix MANTIS Liquid Handler: The MANTIS automated liquid handler increases the reproducibility, throughput and efficiency of our RNA-seq workflows. It uses a diaphragm-based chip design and is thus liquid class compatible, dispensing aqueous and organic solutions of varying viscosities down to 100nL at CV < 3%. Efficiency is enhanced via reaction miniaturization as well as reduced dead volumes and tip consumption.

10x Genomics Chromium X: The Chromium Controller uses microfluidics to perform single cell partitioning and barcoding in minutes. It is highly efficient (thus reducing RA time), robust for both single cell and single nucleus samples), with increased replicability (easier interface provides reduced variability between experiments), wide applicability across tissue types (has successfully produced data across a spectrum of tissues including nervous system, adipose, pancreas, liver, endothelial cells, muscle), and flexible (stand-alone single-nucleus ATAC-seq as well as simultaneous single cell multi-ome ATAC + Gene Expression kits are now available), with excellent company support.

***We also support instrument-free single cell platforms like Parse Bio and Fluent (recently acquired by Illumina)***

Miltenyi Biotec GentleMacs Dissociator: The gentleMACS dissociator is a benchtop instrument for semi-automated dissociation of tissues into single-cell suspensions. The gentleMACS Tubes used with the instrument enable the time-saving and reproducible homogenization of tissues in a closed system, and have improved reproducibility our single cell/single nucleus experiments. Specific programs have been developed for various tissues and standardized tissue dissociation and homogenization procedures, enabling reliable and reproducible results.

Illumina NextSeq 500 high-throughput sequencer (SUNSET 2025): The NextSeq 500 is a high-throughput benchtop sequencer capable of whole-genome sequencing, exome sequencing, RNA-seq, single-cell and single-nuclei RNA-seq, methylation sequencing, and many others. Users can choose between high output or mid output flow cell configurations. At high output, up to 800 million paired-end reads can be generated (at 150 bp read length) to produce up to 120 Gb of data in 29 hours. The Illumina sequencing systems utilize a well-established sequencing by synthesis (SBS) method in which fluorescently labeled nucleotide bases are detected as they are incorporated into DNA template strands. All four reversible terminator-bound dNTPs are present in each sequencing cycle; this feature minimizes bias of incorporation and greatly reduces raw error rates.

Invitrogen Qubit 3 Fluorometer: Automated system for quantification of DNA and RNA samples. The fluorescent dyes used in the Qubit assays emit signals only when bound to specific target molecules, which minimizes the effects of contaminants, including degraded DNA or RNA. This assay is more sensitive and specific than UV spectrophotometry.

Extensive Q-PCR capabilities: (1 Applied Biosystems QuantStudio 5 Real-Time PCR System, and 1 QuantStudio 6 Flex Real-Time PCR System).