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We are the only lab in Boston to run the highly multiplex 11,000-protein SomaScan v5.0 assay.
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The BIDMC Biomarker Discovery Center has over 20 years of experience in precision medicine and proteomics biomarker discovery in tissue and biological fluids.

SomaScan Aptamer Proteomics Platform

  • All biological fluids: serum/plasma (35 ul), CSF (15 ul), urine, synovial fluid, etc.
  • All exosomes, cell and tissue extracts (2.4 ug of protein)
  • Designed for human proteins; works well for other species (primates, mouse, rat, pig, sheep)

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Services

  • SomaScan Biomarker Discovery
  • ELISA confirmation using the Ella cartridge microfluidic assay
  • In-depth bioinformatics and systems biology analysis
  • Grant & paper writing advice, consultation and collaboration

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Equipment

  • SomaScan Tecan Fluent liquid handling robot
  • Agilent SureScan  microarray scanner (Model D)
  • BioTEK SynergyMX  plate reader
  • Biotechne Ella fully automated multiplex immunoassay platform
  • Ingenuity (IPA) pathway analysis

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State-of-the-Art Technologies

  • Proteomics
  • Transcriptional profiling
  • Genotyping
  • Real-time-PCR
  • Robotics

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Recent Customer Publications Utilizing Our Core Services

  • Nurse’s Health Study (BIDMC and HSPH), Proteomics (2022).
  • Endometriosis (BIDMC and BWH), Human Reproduction (2022, 2023), Am J Obstet Gynecol. (2024).

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