About

Beth Israel Deaconess Medical Center/Harvard Medical School

Stem Cell and Organoid Research and Engineering (SCORE) Center

We have the unique ability to use tissues from organ donors, with the support of the newly created BIDMC/New England Donor Services (NEDS) hospital-based Donor Care and Recovery Center, in combination with differentiated stem cells, to create a multicellular 3D organoid. This allows us to obtain organoids that include all the cellular microenvironment and components that one can find in the real organ. This new concept will transform the way regenerative medicine and drug discovery are classically intended. Having multicellular 3D organoids that recapitulate at micro tissue level the organ, will allow us to study more precisely diseases that could not be defined until now because of the lack of similarities between the in vitro derived organoids and the real tissue. Moreover, having the ability to derive human induced pluripotent stem cells (hiPSCs) directly from the patient’s tissue, will make our Center a source for personalized medicine, allowing for the discovery of more efficient therapeutic options.

For more information please contact Giuseppe Pettinato to discuss how multicellular organoids generation can help your research.