The Department of Psychiatry at Beth Israel Deaconess Medical Center is inviting women ages 40-60 to participate in a research study investigating how pregnenolone affects the brain in perimenopausal women who are experiencing depression. We are studying this by giving women pregnenolone that is available as an oral over-the-counter dietary supplement in the US and has been shown to have a potential therapeutic benefit for depression in a previous clinical trial involving treatment with pregnenolone or placebo. Participation includes 4 outpatient study visits. Study procedures may include blood draws, MRI scans, questionnaires, and completing daily diaries for up to 4 weeks. Participants will be compensated up to $1,600 upon completion of all study procedures.
Please complete the survey below to help determine if you might be eligible to participate in this study. A research coordinator will be in touch with you if you are eligible for further screening.
For more information, please contact the study coordinator at bidmc-sadiestudy@bidmc.harvard.edu or
Principal Investigator: Hadine Joffe, MD MSc
