Hadine Joffe, MD, MSc

Hadine Joffe, MD, MSc is the Chair and Psychiatrist-in-Chief of Department of Psychiatry at Beth Israel Deaconess Medical Center and the Paula A. Johnson Professor of Psychiatry in the Field of Women’s Health at Harvard Medical School, who previously served as the Executive Director of the Connors Center for Women's Health Research at Brigham and Women's Hospital. She is a clinical reproductive neuroscientist and academic psychiatrist whose research has advanced understanding and treatment of depression, sleep, and related neurocognitive symptoms in midlife women and breast cancer survivors. Dr. Joffe’s research focuses on the mechanisms, course, and treatment of depression, insomnia, thermoregulatory symptoms, and fatigue in women navigating the menopause transition or undergoing breast cancer treatment. She has led NIH-funded studies for over 26 years, including as Principal Investigator on three R01s and a U54 Specialized Center of Research Excellence (SCORE) focused on sex differences in health and disease.

 

Her work integrates neural, hormonal, neurosteroid, stress, and autonomic pathways to better characterize the biological underpinnings of depression and associated symptoms in midlife women, and their downstream consequences on metabolism and anti-estrogen adherence. Her research excellence has been recognized by the Thomas Clarkson Outstanding Clinical & Basic Science Research Award and the Vivian Pinn Award for Outstanding Research in Women’s Health from The Health of Women National Society.

 

Dr. Joffe is a committed mentor, having supported the careers of over 100 investigators and clinicians. Her contributions have been recognized through the Harvard Medical School William Silen Lifetime Achievement in Mentoring Award and the Harvard Medical School Department of Psychiatry Stuart T. Hauser MD PhD Mentorship Award.