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Diet-induced obesity

Analysis of diet-induced obesity experiments in male C57Bl/6J mice on a low-fat diet (LFD) or high-fat diet (HFD), demonstrating differences in body weight, energy intake, expenditure, and balance (Banks et al., Nature Metabolism, 2025). ​

Optogenetic stimulation of food intake

Optogenetic stimulation of Agrp neurons in ChR2-expressing mice was performed in the Promethion calorimeter, with food intake, metabolic rate, body temperature, and activity measured during the stimulation period.

Services

Energy Balance Metabolic Core at BIDMC and Harvard Medical School is a facility designed for the measurement of energy intake, nutritional status, and energy expenditure in experimental mice. CalR Equipment & Technologies Example Experiments

Other Systems

PARR Instruments Bomb Calorimeter Determines energy content of food or fecal matter FLIR Thermal Imaging Camera Determines thermal radiation

Publications

Highly Cited Research from the Core Many discoveries have relied upon careful measurement of body composition and metabolic rates in un-anesthetized, freely moving mice. One metric to determine the impact of a scientific publication is how many times other scientific articles have referred to that...

For Participants

Study: Infant Vaccine Biorepository Nickname: IVB In this study, infants from all over the US contribute to science by providing a home-collected (tiny) blood sample. 180 enrolled to date Funding: BIDMC Hub Spark Grant, Massachusetts Consortium for Pathogen Readiness (MassCPR), Harvard University...

Simon Center for Outcomes Research and Improvement (rCORI)

Celebrating Innovation and Exploration at the Annual Morris Simon Research Day Recent and Historical Award Recipients | Simon Day Presentations and Posters On June 3, 2025, the Department of Radiology hosted the 9th Annual Morris Simon Research Day in the Klarman Conference Center at BIDMC Boston...