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Relaxin-2 as a Novel Protein Therapeutic for the Treatment of Arthrofibrosis: Treatment options for arthrofibrosis are limited. Specifically, treatment for shoulder arthrofibrosis requires months to years of physical therapy or even surgical procedures. Relaxin is a hormone that is primarily...

Prior work by others suggests that renal nerves arise from several neuron subpopulations in sympathetic ganglia. It is possible that these specific subpopulations of neurons, as well as the CNS circuits that innervate them selectively control tubular transport, glomerular filtration rate or renin...

Hedonic Capacity, Psychosocial Interventions and Outcomes in Schizophrenia

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This project aims to establish a repository of biosamples in patients with varying neurologic disorders. The proposed biorepository aims to collect a variety of high-quality biosamples and relate them to clinical information to support the accelerated identification of disease biomarkers for earlier...

We have successfully identified multiple novel genetic associations between AD and common and rare variants in endolysosomal genes ( PLD3, RAB10, GRN12, TMEM106B, CPAMD8, MS4A4A). Recently, we performed a systematic, comprehensive evaluation of the contribution of coding variants in each...