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Young-Bum Kim, Ph.D. Professor of Medicine, Harvard Medical School Principal Investigator, Division of Endocrinology, Diabetes & Metabolism, Beth Israel Deaconess Medical Center (BIDMC) Dr. Kim’s research centers on the molecular control of glucose and energy homeostasis in conditions such as...

The Kim Laboratory investigates molecular and physiological mechanisms that regulate glucose and energy homeostasis, with a focus on pathways that are disrupted in obesity, type 2 diabetes and fatty liver disease. We concentrate on key signaling nodes, including the kinase ROCK1, the lipoprotein...

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The Lawler lab has studied the structure and function of the members of the TSP gene family for more than 50 years. We have focused on the role of TSP-1 in the tumor microenvironment. This research has informed the development of a new cancer therapeutic that is currently being evaluated in murine...

C57Bl/6J male mice were monitored in the Promethion indirect calorimeter, and data were analyzed in CalR to compare energy expenditure between T3-treated and vehicle groups (Hochbaum et al., Cell, 2024).

Mice expressing DREADDs and non-DREADD controls were monitored in the Promethion indirect calorimeter, with CNO administered at hour 4 and data plotted in CalR.