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Mark Zeidel and Warren Hill were part of a large team led by Dr. Gary Churchill at The Jackson Laboratory in Bar Harbor Maine that just published in Nature the results of a study that followed 970 genetically diverse mice over four years. The results showed that caloric restriction and intermittent...

Dr. Secemsky kicked off 2025 with presentations at this year's THT (Boston, MA), LINC (Leipzig, Germany), and ISET (Miami, FL) vascular medicine conferences. His talks included: " Acute PE Risk Stratification: Where Do Hemodynamics Fit In?" (THT), " Bioabsorbable Scaffolds: A Revolution Below the...

A recent Aging Cell publication by Drs. Alice Rodrigues, Jan Heng, and Frank Slack identified miR-30c-5p, found in extracellular vesicles from young mice, as a promising therapeutic for reversing age-related liver fibrosis. The treatment improved insulin sensitivity and extended health span—offering...

This March, members of the Cardiovascular Imaging Section traveled to Chicago to present their research at the American College of Cardiology Conference 2025. Christy Zheng, research student, presented her work assessing technical changes to an algorithm to detect heart failure with preserved...

In a recent Nature Communications study, Dr. Annalisa Di Ruscio and team introduced aptaDiR, a novel RNA therapeutic engineered to silence DNMT1 and reverse abnormal DNA methylation in cancer. Delivered via lipid nanoparticles, aptaDiR reactivated tumor-suppressor genes and significantly reduced...

Warren Hill and his collaborators have just published a paper in Physiological Reports describing the capabilities of a new machine learning program they call ML-UrineQuant. A simple and non-harmful way of looking at bladder function in mice involves placing them on filter paper for 4 hours and then...

Dr. Heng will be a keynote speaker at AI Club's annual Research Symposium. https://corp.aiclub.world/2025-student-research-symposium

Maedeh Niroumand - a rising P1 student at Massachusetts College of Pharmacy & Health Sciences joined us as a research student. We hope that she'll enjoy our research in drug discovery and development. Best of luck Maedeh!

We say farewell to Guiherme today! Thank you very much for your hard work in the past two years. Your computational chemistry expertise was a great asset to our research program. We wish you all the best for your future endeavors!