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Lower urinary tract symptoms (LUTS) including overactive bladder, incontinence and flaccid bladder may be the most common complication for patients with diabetes, affecting up to 80–90% of patients by some estimates. We wanted to know which of the mouse strains with high blood glucose would develop...

Prior studies identify brain/spinal cord regions involved in controlling bladder function, but often do not resolve neuronal subpopulations or their specific connections. We seek to develop in mice a complete circuit map of the control of bladder filling and voiding. Prior work and our own...