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The Detection Unit of the Precision RNA Medicine Core offers two main services: MicroRNA Screening (targeted panels) Our unit offers full service microRNA screening of bio specimens using Mirxes ID3EAL™ assays. This highly sensitive qPCR-based technology can simultaneously screen for up to 376...

The PRM Core is comprised of a team of research technicians, software engineers, database developers and support staff at the doctoral level working under the direction of the PRM Core Directors. PRM staff provide biomedical data analysis, scientific systems administration, software and algorithm...

We can perform delivery of RNA via nanoparticle packaging both in vitro and in vivo using NanoAssemblr technology from Precision NanoSystems.​ ​Using an off-the-shelf lipid (Genvoy-ILM), the core can deliver siRNAs, miRNAs, mRNA, and more. Additionally, clients can use their own lipids and test...

The Precision RNA Medicine (PRM) Core is a state-of-the-art informatics, delivery, and preclinical facility dedicated to precision medicine at Beth Israel Deaconess Medical Center (BIDMC) and Harvard Medical School (HMS). The Core is directed by Associate Professor Win Hide, and is co-directed by...

We provide a broad range of analytical services and grant development support. We analyze high throughput sequencing data, including bulk and snRNA seq, coding and noncoding RNA and genomics. We also provide consultation and support for coding and non-coding RNA research. The core is Directed by Dr...

The PRM Core does not require or request co-authorship on studies using data generated solely by using off-the-shelf software on a fee-for-service basis by our facilities. However, in cases where PRM Core members make significant intellectual contributions, co-authorship follows commonly accepted...