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Join the Lab
Welcome! Please contact Veronique, including sending your curriculum vitae, a brief statement of research experience and interests, and letters of reference. Email: vanderhorstlab@bidmc.harvard.edu
Publications
Celada M, Zaarour N, Cheung J, Gross C, Lim A, Buchman AS, Saberi P, Varma G, VanderHorst V. Standardization of postmortem human brainstem along the rostrocaudal axis to accommodate for inter-specimen structural heterogeneity. Sci Rep. 2025 Oct 15;15(1):36064. doi: 10.1038/s41598-025-20016-7.PMID...
Highly Cited Research from the Core
Many discoveries have relied upon careful measurement of body composition and metabolic rates in un-anesthetized, freely moving mice. One metric to determine the impact of a scientific publication is how many times other scientific articles have referred to that work–or citations. Selected highly...
Our Research Team
Research
The Kim Laboratory investigates molecular and physiological mechanisms that regulate glucose and energy homeostasis, with a focus on pathways that are disrupted in obesity, type 2 diabetes and fatty liver disease. We concentrate on key signaling nodes, including the kinase ROCK1, the lipoprotein...
About
Thermogenesis: beta-adrenergic agonist activation
Male C57Bl/6J mice housed at thermoneutrality were administered the β-adrenergic agonist CL 316,243, and changes in oxygen consumption were continuously measured.
Pharmacologic induction of metabolic rate (T3)
C57Bl/6J male mice were monitored in the Promethion indirect calorimeter, and data were analyzed in CalR to compare energy expenditure between T3-treated and vehicle groups (Hochbaum et al., Cell, 2024).
Chemogenetic stimulation of metabolism
Mice expressing DREADDs and non-DREADD controls were monitored in the Promethion indirect calorimeter, with CNO administered at hour 4 and data plotted in CalR.