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Team

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The PRM Core is comprised of a team of research technicians, software engineers, database developers and support staff at the doctoral level working under the direction of the PRM Core Directors. PRM staff provide biomedical data analysis, scientific systems administration, software and algorithm...

Delivery Unit

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We can perform delivery of RNA via nanoparticle packaging both in vitro and in vivo using NanoAssemblr technology from Precision NanoSystems.​ ​Using an off-the-shelf lipid (Genvoy-ILM), the core can deliver siRNAs, miRNAs, mRNA, and more. Additionally, clients can use their own lipids and test...

About Us

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The Precision RNA Medicine (PRM) Core is a state-of-the-art informatics, delivery, and preclinical facility dedicated to precision medicine at Beth Israel Deaconess Medical Center (BIDMC) and Harvard Medical School (HMS). The Core is directed by Associate Professor Win Hide, and is co-directed by...

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News: August 21, 2024
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Bioinformatics Unit

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We provide a broad range of analytical services and grant development support. We analyze high throughput sequencing data, including bulk and snRNA seq, coding and noncoding RNA and genomics. We also provide consultation and support for coding and non-coding RNA research. The core is Directed by Dr...

Ioannis Vlachos, PhD

Person: Co-Director of Bioinformatics Unit, Director of Spatial Technologies Unit, Associate Professor of Pathology, Harvard Medical School
Meet Dr. Ioannis Vlachos, Ph.D., our director of the Spatial Technologies and Bioinformatics Units within the Precision RNA Medicine Core. He is also an Assistant Professor of Pathology at Harvard Medical School and co-Director of the Bioinformatics Program at the Cancer Research Institute (CRI). Dr...

Frank Slack, PhD

Person: Co-Director of the Precision RNA Medicine Core, Director of Delivery Unit , Director of the Harvard Medical School Initiative for RNA Medicine (HIRM), Shields Warren-Mallinckrodt Professor of Medical Research, Professor of Medicine, Harvard Medical School
Meet Dr. Frank Slack, our Co-Director of the Precision RNA Medicine Core at BIDMC. He is also the Shields Warren Mallinckrodt Professor in the Department of Pathology, and the director of the HMS Initiative for RNA Medicine. Dr. Slack's academic journey began with a BSc from the University of Cape...

Publications

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The PRM Core does not require or request co-authorship on studies using data generated solely by using off-the-shelf software on a fee-for-service basis by our facilities. However, in cases where PRM Core members make significant intellectual contributions, co-authorship follows commonly accepted...