Publications

2025

Imaging, Expert Panel on GYN and OB, Sherelle L Laifer-Narin, Alana Fruauff, Cinthia Cruz Romero, Dorothy I Bulas, Ingrid Burger, Christopher Fung, et al. (2025) 2025. “ACR Appropriateness Criteria® First Trimester Vaginal Bleeding: 2025 Update.”. Journal of the American College of Radiology : JACR 22 (11S): S531-S538. https://doi.org/10.1016/j.jacr.2025.08.043.

Vaginal bleeding is a relatively common occurrence in the first trimester of pregnancy, but can be distressing for both patients and clinicians. Differential considerations include normal intrauterine pregnancy (IUP), a nonviable IUP, an ectopic pregnancy (EP), or much less commonly gestational trophoblastic disease (GTD). Although the diagnosis of EP, nonviable IUP, and GTD is important, it is also crucial to avoid harming potentially normal pregnancies through early medical or surgical treatment. Fortunately, most diagnoses can be made using a combination of ultrasound (US), serum human chorionic gonadotropin levels, and physical examination. When a diagnosis is in question, serial examinations and close clinical evaluation is paramount. Occasionally, MRI of the pelvis without contrast may be helpful in problem-solving for challenging cases, where grayscale US is limited or when there is high concern for nontubal EP. The American College of Radiology Appropriateness Criteria are evidence-based guidelines for specific clinical conditions that are reviewed annually by a multidisciplinary expert panel. The guideline development and revision process support the systematic analysis of the medical literature from peer reviewed journals. Established methodology principles such as Grading of Recommendations Assessment, Development, and Evaluation or GRADE are adapted to evaluate the evidence. The RAND/UCLA Appropriateness Method User Manual provides the methodology to determine the appropriateness of imaging and treatment procedures for specific clinical scenarios. In those instances where peer reviewed literature is lacking or equivocal, experts may be the primary evidentiary source available to formulate a recommendation.

Dawar, Ria, Lars J Grimm, Emily B Sonnenblick, Brian N Dontchos, Kristen Coffey, Sally Goudreau, Beatriu Reig, et al. (2025) 2025. “Breast Remote Reading: Widely Desired But Home Workstations Show No Association With Job Satisfaction Or Burnout.”. Journal of Breast Imaging. https://doi.org/10.1093/jbi/wbaf039.

OBJECTIVE: Understand radiologists' opinions regarding remote breast imaging and determine whether having home workstations is associated with greater job satisfaction or less burnout.

METHODS: A 43-question survey on remote breast imaging was distributed to Society of Breast Imaging members (July 6 to August 2, 2023). Questions regarding job satisfaction and burnout were included. Pearson's chi-squared tests compared demographic variables and responses. Multiple-variable logistic regression assessed associations between home workstations and job satisfaction or burnout.

RESULTS: In total, 424 surveys were completed (response rate 13%, 424/3244). Among the third (31%, 132/424) of breast imaging radiologists with home workstations, top motivations included flexibility/work-life balance (67%; 88/132) and decreased commute time (51%, 67/132). Most felt that working from home improved their efficiency (65%, 86/132). Perceived drawbacks among all breast imaging radiologists included the inability to perform US or physical examination (71%, 300/424) and impaired patient contact (47%, 198/424). Most (57%, 240/424) wished for more breast imaging remote reading opportunities, and one-third (32%, 136/424) saw themselves in a 100% remote reading practice in the future. The majority (60%, 228/388) felt that remote reading would majorly or moderately improve radiologist wellness, but no significant association was found between having home workstations and job satisfaction (P = .301) or burnout (P = .140).

CONCLUSION: The majority of breast imaging radiologists want more opportunities to work remotely, perceiving that it improves work-life balance and efficiency, albeit at the expense of patient contact. However, those currently working from home did not have higher job satisfaction or lower burnout.

Dwan, Dennis, Christina Konstantopoulos, Tejas S Mehta, Alexander Brook, Vandana Dialani, Valerie J Fein-Zachary, Evguenia Jane Karimova, Parisa Lotfi, Rashmi J Mehta, and Jordana Phillips. (2025) 2025. “Contrast-Enhanced Mammography: Does Image Acquisition Time and Projection Order Matter?”. Journal of Breast Imaging. https://doi.org/10.1093/jbi/wbaf033.

OBJECTIVE: To determine reader preference for image order and thus, by inference, image timing after contrast administration that maximizes cancer visualization on contrast-enhanced mammography (CEM).

METHODS: This IRB-approved reader study includes consecutive CEMs performed for research or clinical care in patients before a diagnosis of unifocal breast cancer, where the cancer was seen on both craniocaudal (CC) and mediolateral oblique (MLO) recombined images. All CEMs started with the side containing cancer and alternated with the nonaffected side of the same projection. From 2016 to 2018, CC projection was performed first (group 1), and from 2019 to 2020, the MLO projection was performed first (group 2). Five readers evaluated cases for background parenchymal enhancement (BPE) and lesion type. Readers assessed cancer visibility, confidence in margins, and cancer conspicuity using a 5-point Likert scale. Contrast-to-noise (CNR) measurements were also taken.

RESULTS: Seventy-eight female patients were included. Group 1 (CC-first) included 40 patients (51%) and group 2 (MLO-first) included 38 patients (49%). Mean age differed between groups by 5 years (P = .031), otherwise there were no differences in group characteristics. There was an overall preference for earlier-obtained images for cancer visibility, confidence in margins, and lesion conspicuity against BPE (P < .001) and preference for CC projection for lesion conspicuity (P = .045). In 35 instances (35/390, 9%), an individual reader reported a different lesion type on images obtained later, with a majority (28/35, 80%) reporting a less discernible lesion on later-obtained imaging (eg, mass changed to nonmass enhancement).

CONCLUSION: Our study shows significant reader preference for cancer characteristic evaluation of CEM performed at earlier time points.

King, Ben G, Nishat Bharwani, William Wilson, Gary J R Cook, Aslam Sohaib, Marielle Nobbenhuis, Victoria Warbey, et al. (2025) 2025. “Diagnostic Performance of Quantitative Measures from [18F]FDG PET/CT, [18F]FEC PET/CT, and DW-MRI in the Detection of Lymph Node Metastases in Endometrial and Cervical Cancer: Data from the MAPPING Study.”. European Journal of Nuclear Medicine and Molecular Imaging. https://doi.org/10.1007/s00259-025-07587-3.

PURPOSE: To evaluate the diagnostic performance of quantitative measures derived from [18F]FDG PET/CT, [18F]FEC PET/CT, and DW-MRI in the detection of lymph node metastases in endometrial and cervical cancer with comparison to standard visual PET analysis with histology as the reference standard.

METHODS: Subanalysis of quantitative data from the prospective multicentre MAPPING study. Nodal and tumour SUVmax from [18F]FDG PET/CT and [18F]FEC PET/CT and ADCmean from DW-MRI were documented. Nodal-to-tumour ratios (NTR) and SUVmax-to-ADCmean ratio (STAR) were calculated. Optimal cut-offs of quantitative measures were compared to visual assessment on a regional basis using histopathology as the reference standard.

RESULTS: Scans from 112 patients (36 cervical and 76 endometrial cancers; 340 nodal regions) were eligible for quantitative image analysis. Lower ADCmean on DW-MRI was observed in metastatic nodes for cervical cancer but not for endometrial cancer. Quantitative measures were significantly higher in malignant than benign nodal regions on [18F]FDG PET/CT and [18F]FEC PET/CT in endometrial cancer. SUVmax cut-offs showed similar performance to visual assessment in the diagnosis of metastatic lymph nodes in endometrial cancer whilst ADCmean cut-offs showed significantly lower specificity than visual assessment. Interobserver agreement was excellent for SUVmax measurements on both [18F]FDG PET/CT and [18F]FEC PET/CT, but poor for ADCmean on DW-MRI.

CONCLUSION: Quantitative measures from [18F]FDG PET/CT, [18F]FEC PET/CT, or DW-MRI did not outperform visual assessment in the detection of nodal metastases in endometrial cancer. Therefore, the implementation of these quantitative measures as standalone diagnostic tools in routine clinical practice is not recommended.

Bulman, Julie C, Stephanie L McNamara, Jeffrey L Weinstein, Nazia Kazim, Wafa Q Khan, and Ammar Sarwar. (2025) 2025. “Utilization of Arterial and Venous Thrombectomy in the United States: A 6-Year Evaluation of Medicare Claims.”. Journal of the American College of Radiology : JACR. https://doi.org/10.1016/j.jacr.2025.09.007.

PURPOSE: The aim of this study was to understand the utilization of arterial thrombectomy (AT) and venous thrombectomy (VT) by provider specialty, region, and diagnosis code in the Medicare population.

METHODS: Common Procedural Terminology (CPT) codes 37184 to 37188 claims for AT and VT between January 2017 and December 2022 were analyzed from the Medicare standard analytic file 5% sample claims database. Data fields included provider specialty, geographic region, place of service, and number of procedures. A secondary analysis was performed of thrombectomy claims by International Classification of Diseases, 10th rev, codes for venous thromboembolism (VTE) or arterial thromboembolism.

RESULTS: Thrombectomy claims increased by 38%, with a 137% increase in VT (compound annual growth rate [CAGR] +19%) compared with a 7% increase in AT (CAGR +1%). Dominant VT specialties were radiology (34%), surgery (29%), and cardiology (20%). Dominant AT specialties were surgery (41%), cardiology (35%), and radiology (17%). Cardiology demonstrated a 19% decrease in AT (CAGR -4%), whereas radiology experienced a 47% increase (CAGR +5%). The majority of AT and VT claims were performed in the Southeast and Midwest, accounting for 62% of AT and 57% of VT. Dominant place of service for both AT and VT was outpatient hospital (76% of AT, 78% of VT). International Classification of Diseases, 10th rev, analysis demonstrated a 712% increase in AT claims for pulmonary embolism (CAGR 52%).

CONCLUSIONS: VT and AT for VTE continue to rise at a higher rate than non-VTE claims, with a 712% increase in AT for pulmonary embolism and 137% increase in VT. Radiology remains the dominant VT specialty and experienced the greatest increase in AT claims as a specialty.

Bar, Nitai, Ronald L Eisenberg, Yuval Liberman, Aurelija Liubauske, Ivan D Queiros, Jennifer M Cutts, Jonathan Revels, Tami J Bang, and Diana E Litmanovich. (2025) 2025. “Evaluating the Status of Cardiac Imaging Training in Radiology Residency Programs in the United States.”. Journal of Thoracic Imaging. https://doi.org/10.1097/RTI.0000000000000856.

PURPOSE: Cardiac imaging is an integral part of modern diagnostic imaging and a subject heavily tested on the Radiology Core exam. Therefore, radiology residency programs should provide adequate training in this area. This study aims to investigate the current state of cardiac imaging training within radiology residency programs in the United States.

MATERIALS AND METHODS: Survey questionnaires using the Research Electronic Data Capture (REDCap) platform were sent to heads of cardiac/cardiothoracic sections in all US radiology residency programs for which valid email addresses were available.

RESULTS: Of 163 questionnaires sent, there were 70 responses, with 82.9% completing the entire survey. In total, 85.9% reported having a cardiac imaging rotation, with 58.8% being 4 weeks, mostly in a single block. Sixteen programs (31.4%) offered a longer cardiac experience (6 to 12 wk). In total, 90.7% reported having a designated person responsible for cardiac imaging, a radiologist in 68.5% and a combined radiologist and cardiologist in 22.2%. The responsible person for reporting cardiac CT was a radiologist in 40.7%, with a combined radiologist and cardiologist in 59.3%. For cardiac MRI studies, there was combined responsibility in 69.0%, either on alternate days of coverage or with the radiologist interpreting noncardiac findings. A total of 65.5% reported having ≥6 cardiac case conferences yearly, and 75.9% had ≥6 cardiac lectures. In total, 65.6% of programs offered cardiothoracic fellowships, with 87.2% dedicating ≥3 months to cardiac imaging. Only 18.6% had dedicated cardiovascular fellowships.

CONCLUSION: Our research offers crucial insights into the current trends in cardiac imaging education and practice within radiology residency programs, so that professional societies can develop guidelines to structure a more uniform and thorough approach toward cardiac imaging education.

Tannenbaum, Melissa F, Karen S Lee, Se-Young Yoon, and Robin B Levenson. (2025) 2025. “Lessons Learned in Emergency Pelvic and First-Trimester US: Focus on Cognitive Biases.”. Radiographics : A Review Publication of the Radiological Society of North America, Inc 45 (2): e240101. https://doi.org/10.1148/rg.240101.

Nonpregnant and pregnant women who present with acute pelvic pain can pose a diagnostic challenge in the emergency setting. The clinical presentation is often nonspecific, and the differential diagnosis may be very broad. These symptoms are often indications for pelvic US, which is the primary imaging modality when an obstetric or gynecologic cause is suspected. Interpretation of pelvic US may be challenging and a source of confusion and misinterpretation for radiologists. Additionally, cognitive biases in imaging interpretation can contribute to diagnostic errors. Cognitive biases represent systematic errors due to failure of the mental shortcuts that the brain subconsciously uses to produce quicker judgments. There are multiple different types of cognitive biases, all of which may lead to perceptual and interpretive errors. Familiarity with common and uncommon pelvic US findings in the setting of pelvic pain is imperative to assist with prompt and accurate diagnosis. Awareness of potential biases when interpreting pelvic US findings further helps hone the interpretation. The authors illustrate the imaging findings in several peer learning cases of nonpregnant and first-trimester pregnant patients who presented with acute pelvic pain in the emergency setting. Several nonobstetric and nongynecologic causes of acute pelvic pain are included for which pelvic US was the first imaging modality used in diagnosis. Diagnostic errors and cognitive biases in interpretation related to these cases are highlighted. The radiologist's awareness of potential cognitive biases in image interpretation may help to refine the differential diagnosis and mitigate errors. ©RSNA, 2025 Supplemental material is available for this article.