Sleep and Light Resource Core

The Sleep and Light Resource Core (SLRC) will be integrated into this SCORE by providing equipment, analysis, sleep- and light-related expertise, and sleep and light data to the two human, one animal, and relevant Career Enhancement Core projects. The scientific leadership and technical support to facilitate and integrate rigorous collection, processing, analysis, and interpretation of sleep and light measures, will enable the SLRC to promote interdisciplinary, collaborative, synergistic, and translational work and support the scientific and career enhancement goals of this SCORE. This work will expand the scientific impact of the SCORE by including sleep as a key health measure in human and animal models of women’s health and aging, including impacts on response to stress; body composition; neurological, cardiovascular, reproductive, and metabolic function; cognition; and mental health.

Core Publications

*ROSA Affiliated Authors shown in bold

“Keeping an eye on circadian time in clinical research” Clinical and Translational Medicine. Klerman EB, Brager A, Carskadon MA, Depner CM, Foster R, Goel N, Harrington M, Holloway PM, Knauert MP, LeBourgeois MK, Lipton J, Merrow M, Montagnese S, Ning M, Ray D, Scheer FAJL, Shea SA, Skene DJ, Spies C, Staels B, St-Onge MP, Tiedt S, Zee PC,  Burgess HJ.

“From Bench to Bedside and Back Again: translating circadian science to medicine” Journal of Biological Rhythms. Klerman EB, Kramer A, Zee PC.

“Beyond the symptom: the biology of fatigue” SLEEP. Raizen DM, Mullington J, Anaclet C, Clarke G, Critchley H, Dantzer R, Davis R, Drew KL, Fessel J, Fuller PM, Gibson EM, Harrington M, Lipkin WI, Klerman EB, Klimas N, Komaroff AL, Koroshetz W, Krupp L, Kuppuswamy A, Lasselin J, Lewis LD, Magistretti PJ, Matos HY, Miaskowski C, Miller AH, Nath A, Nedergaard M, Opp MR, Ritchie MD, Rogulja D, Rolls A, Salamone JD, Saper C, Whittemore V, Wylie G, Younger J, Zee PC, Heller HC.

“Consensus Recommendations for Standardized Data Elements, Scales, and Time Segmentations in Studies of Human Circadian/Diurnal Biology and Stroke” Stroke. Saver JL, Klerman EB, Buchan AM, Calleja P, Lizasoain I, Bahr-Hosseini M, Lee S, Liebeskind DS, Mergenthaler P, Mun KT, Ning M, Pelz D, Ray D, Rothwell PM, Seners P, Sreekrishnan A, Sung EM, Tiedt S, Webb AJS, Wölfer TA, Albers GW; CIRCA.

“The organization of sleep-wake patterns around daily schedules in college students” SLEEP. Lu S, Stone JE, Klerman EB, McHill AW, Barger LK, Robbins R, Fischer D, Sano A, Czeisler CA, Rajaratnam SMW, Phillips AJK.

Core Leader


Division of Sleep and Circadian Disorders
Brigham and Women’s Hospital
Harvard Medical School

 

Core Investigators


Division of Sleep and Circadian Disorders
Brigham and Women’s Hospital
Harvard Medical School

 

Department of Neurology
Beth Israel Deaconess Medical Center
Harvard Medical School

 

Department of Neurology
Beth Israel Deaconess Medical Center
Harvard Medical School