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Imaging for Risk Assessment in Multiple Clinical Scenarios
Many decisions that general clinicians need to make daily are based on a risk assessment of different clinical (medical or surgical) interventions relative to the risk of non-intervention. We have a program for developing imaging protocols to better assess risk for patients in several clinical...
Research & Education
About Jack Lawler
CalR
Go to CalR, a web application for indirect calorimetry analysis. The CalR project: There is a critical lack of standardization for indirect calorimetry experiments to measure body composition ( Corrigan et al eLife 2020, Banks et al Nature Metabolism 2025). Currently, the same dataset can produce...
Thermogenesis: beta-adrenergic agonist activation of mice housed at thermoneutral temperatures
Male C57Bl/6J mice housed at thermoneutrality were administered the β-adrenergic agonist CL 316,243, and changes in oxygen consumption were continuously measured.
Quantitation rates of substrate oxidation in vivo using stable isotope tracing
In vivo stable isotope tracing with U-¹³C₆ D-mannitol and U-¹³C₆ D-glucose was conducted to enable ¹³CO₂ monitoring in the Promethion indirect calorimeter, with data plotted using CalR for conventional (blue) and commensal-depleted (red) mice (Vieira et al., in press).
Principal Investigator
Alexander S. Banks, Ph.D. Assistant Professor asbanks [at] bidmc.harvard.edu About Dr. Banks Investigations in the Banks lab focus on understanding the mechanisms linking obesity with insulin resistance. The goal of this work is to provide new insights that may lead to novel therapeutic...
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MEMS Deformable Mirror Zoom
DMs at fixed locations in an optical microscope imaging system was used to provide 2.5x zoom capability, dynamic focus control, and aberration compensation. Zoom is achieved by simultaneously adjusting focal lengths of the two DMs, which are inserted between an infinity-corrected microscope...