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About Us

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The Structural Biology Core Facility at Beth Israel Deaconess Medical Center, located at 99 Brookline Avenue (Research North), was established to provide state-of-the-art support for investigators across BIDMC, Harvard Medical School, and the broader biotechnology and pharmaceutical communities. Our...

Structural Biology Core

The Structural Biology Core Facility at BIDMC, Our core specializes in the expression, purification, and characterization of high-quality proteins for use in structural biology—including Cryo-Electron Microscopy and X-ray Crystallography—as well as a wide range of biochemical, biophysical, and therapeutic development applications.

Jerome Groopman, MD

Person: Scientific Advisor of Structural Biology Core, Dina and Raphael Recanati Professor of Medicine, Harvard Medical School

Gabriel Birrane, PhD

Person: Director of Structural Biology Core, Instructor in Medicine, Harvard Medical School

Equipment and Technologies

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Our facility is equipped with a comprehensive suite of modern instruments supporting the full pipeline—from protein expression and purification to crystallography, biophysical characterization, and advanced structural determination: Protein Expression & Cell Culture Eppendorf S41i CO₂ Shaker...

Community

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The Structural Biology Core Facility at BIDMC has served the scientific community for more than 18 years, supporting academic laboratories, startups, and global pharmaceutical partners from early concept through successful execution. We foster a collaborative and interdisciplinary environment by...

Services

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Our facility offers comprehensive, end-to-end support for protein production, structural biology, and biophysical characterization—whether your goal is basic research, drug discovery, or translational development. Molecular Biology & Cloning Custom cloning of your gene of interest into a wide range...