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Functional MRI Processing for Mouse Micturition Studies Functional MRI (fMRI) studies in rodents is somewhat uncommon as it requires some cognitive or physiological stimulus that causes measurable changes in brain activity. This project however, lends itself well to fMRI studies as voiding induced...

Team And Collaborators: Mark Zeidel, MD, Principal Investigator Bryce MacIver, PhD, Project Coordinator Aaron Grant, PhD, Director, Preclinical MRI Core at BIDMC Dave Alsop, PhD, Director, Division of Magnetic Resonance Research at BIDMC Cody Callahan, BS, Department of Radiology at BIDMC John Mac...

These studies were funded by an NIH P20 grant [DK108276], to form a Resource Development Project within the BIDMC Department of Medicine’s Center for Interdisciplinary Research in Benign Urology. This Project brings together Department of Radiology Magnetic Resonance Imaging (MRI) physicists and...

Name Date Current Position Ali Wu, MD Erandi Velaquez-Miranda, PhD Lian Yu Guo, PhD Reina Kobayashi, DVM

In our laboratory, we investigate the finely tuned neural control mechanisms that govern voiding and continence in the bladder. Our aims are to map the circuits, create neural atlases of neuron sub-populations and then determine what each type of neuron does. Our investigators are performing basic...

Modern transgenic “tools” enable specific neuron populations to be mapped, monitored, and manipulated in vivo. While these approaches represent an enormous advance, their application requires knowledge of specific transcriptional markers for distinguishing the neurons of interest from their...