How does epigenetics cause and cure cancer?

Our lab develops and applies cutting-edge genomics technologies to advance cancer cure

About Us

Research

Research Areas

Our research centers on three fundamental questions:

How does epigenetic change contribute to tumorigenesis?
What epigenetic vulnerability can we target to develop a novel therapy?
How do epigenetic drugs work?

Tumorigenesis

tumor_development

How does epigenetic change contribute to tumorigenesis?

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New Targets

target

What epigenetic vulnerability can we target to develop novel therapy?

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Drug Mechanism

drug

How do epigenetic drugs work?

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Lighting the way

Forefront of Research

We use cutting-edge next- and third-generation sequencing technologies, integrated with powerful computational tools, to decode the epigenetic landscapes of cancer.

Our Team on The Forefront of Research

We are a collaborative team of experimental and computational researchers with expertise in cancer biology, molecular biology, biochemistry, epigenetics, neuroscience, and computer science.

Our Latest Updates

Dr. Wu was awarded the NCI Transition Career Development Award (K22)

September 01, 2025

Dr. Jingyi Wu, Assistant Professor of Medicine at Beth Israel Deaconess Medical Center and Harvard Medical School, has been awarded the prestigious National Cancer Institute (NCI) Transition Career...
Study Reveals Chromatin-Based Mechanisms of Epigenetic Therapy

August 01, 2025

A new collaborative study led by scientists from the Broad Institute of MIT and Harvard, Dana-Farber Cancer Institute (DFCI), and Beth Israel Deaconess Medical Center (BIDMC) has uncovered how two...
Study Reveals How Slow-Growing Brain Tumors Evolve into Deadly Cancers

January 20, 2025

A collaborative team led by Dr. Jingyi Wu at the Dana-Farber Cancer Institute and Massachusetts General Hospital has revealed how epigenetic and genetic forces drive the deadly progression of IDH...