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Our lab is very proud of all of those who have spent time here. Their efforts have been integral in our collective successes. We celebrate their accomplishments and the role they continue to play inside, and outside, the scientific community. Our Alumni: Postdoctoral / Research Fellows...

See our most recent relevant publications below. To browse all publications, click the "more" button at the bottom of the list. For a complete list of Dr. Bouxsein's publications: Dr. Bouxsein's Google Scholar Page For a complete list of Dr. Johannesdottir's publications: Dr. Johannesdottir's Google...

For several years, we have been exploring the factor-of-risk concept to understand the unique pathophysiology of vertebral fractures. Using computed tomography (CT) scans from the Framingham Heart Study, we have explored the relationship between spinal curvature, trunk muscle, and vertebral strength...

Our lab offers a variety of services, ranging from mechanical testing to high resolution imaging. If you are interested, please visit the specific page, by clicking on the image or selecting from the dropdown menu above, for more information on the background and contact information for each service...

Our research focuses on understanding musculoskeletal health, particularly in the context of aging, osteoporosis, diabetes (T1D and T2D). We employ advanced non-invasive and in vivo quantitative imaging techniques, along with ex vivo bone specimen analyses and preclinical studies, to assess bone and...

Although imaging is often used as a surrogate to evaluate bone fragility, direct measurements of mechanical strength are undoubtedly the gold standard for providing information about the mechanical integrity of bone. Our lab offers a variety of mechanical testing options for measuring the mechanical...

Micro-computed tomography (microCT) is an imaging technique that uses x-rays to produce cross-sectional images of an object that can be reconstructed to create a three-dimensional model. It allows for non-destructive quantitative analysis of the density, geometry and microarchitecture of mineralized...

As part of our assessment of tissue properties, we perform microindentation using a BioDent tester, which is a novel reference point indentation device developed by ActiveLife Scientific. Reference Point Indentation enables assessment of bone material properties without requiring special surface...

We recognize the value of collaborations and are proud of our many collaborators, both current and past. Collaboration is at the heart of scientific progress, and we are happy to highlight some of our collaborations below: San Francisco Coordinating Center, The Osteoporotic Fractures in Men (MrOS)...

Our research focuses on mitigating the deleterious effects of spaceflight on the skeleton. Using both clinical investigations in astronauts and experimental studies in animal models, we examine how microgravity disrupts bone remodeling, compromises skeletal integrity, and alters cellular and...