Research
Research at the Singhal Laboratory
Mission Statement
To foster a supportive environment where every voice is equally valued, and integrity is upheld.
To bring objectivity to lymphatics by posing and addressing questions that are bold and scientifically sound.
To prevent the development of lymphedema after high-risk operations
Our Research
This laboratory's focus is on lymphatic anatomy and function, treating lymphedema and preventing the development of lymphedema after high-risk operations. View a map of the lymphatic system (published by our team August 1, 2023), adapted from Anatomy of the Human Lymphatic System (1938) by H. Rouvière.
Current Studies
Open protocols include a biorepository of samples from surgical patients, and studies with extramural funding including Variable Anatomy & Function and the Lymphatic Tissue Mapping Center from HuBMAP.
Fig. 2. Schematic demonstrating the variability in connections from the forearm lymphatic channels (yellow) to the tricipital pathway (red) with the long-bundle scenario A indicating a functional connection from one or both forearm channels, whereas the short-bundle scenario B is visualized after the targeted ICG injection (red dot) over the tricipital pathway. Published in Friedman R, Bustos VP, Pardo J, et al. Superficial and functional imaging of the tricipital lymphatic pathway: a modern reintroduction. Breast Cancer Res Treat. 2023;197(1):235-242. doi:10.1007/s10549-022-06777-z
Publications
Manuscripts from this lab tend to fall in these categories:
Watch Dr. Singhal present on Immediate Lymphatic Reconstruction
Dr. Singhal discussing Immediate Lymphatic Reconstruction (ILR, also known as LYMPHA) at the Boston Lymphatic Symposium in November 2018