Ganesh, S., Bhattacharya, R., Bhatnagar, A., Madnani, R., Russo, C., Haidermota, S., Oruganty, B., Bhavsar, H., Shah, P., Pitafi, S., Uppal, N., Sengupta, N., Rice, K., Conomos, M. P., Dave, R., Khandelwal, A., Patel, A. P., Paruchuri, K., Levitsky, Y., … Natarajan, P. (2026). The OurHealth Study: A digital genomic cohort for cardiometabolic risk mechanisms in US South Asians.. NPJ Digital Medicine, 9(1), 151.
Abstract
South Asians experience disproportionately elevated cardiometabolic disease risk yet remain underrepresented in genomic research. The OurHealth Study builds a digital biobank of US South Asian adults, integrating remote surveys, mailed biospecimens for sequencing, and electronic health record sharing to identify genetic and non-genetic drivers of cardiometabolic disease. By pairing remote participation with culturally tailored outreach, OurHealth enhances accessibility, supports granular phenotyping, and addresses logistical barriers to genomic research inclusion.