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Modern transgenic “tools” enable specific neuron populations to be mapped, monitored, and manipulated in vivo. While these approaches represent an enormous advance, their application requires knowledge of specific transcriptional markers for distinguishing the neurons of interest from their...

In our laboratory, we investigate the finely tuned neural control mechanisms that govern voiding and continence in the bladder. Our aims are to map the circuits, create neural atlases of neuron sub-populations and then determine what each type of neuron does. Our investigators are performing basic...

Prior studies identify brain/spinal cord regions involved in controlling bladder function, but often do not resolve neuronal subpopulations or their specific connections. We seek to develop in mice a complete circuit map of the control of bladder filling and voiding. Prior work and our own...

Prior work by others suggests that renal nerves arise from several neuron subpopulations in sympathetic ganglia. It is possible that these specific subpopulations of neurons, as well as the CNS circuits that innervate them selectively control tubular transport, glomerular filtration rate or renin...

Daniel Sanchez-Almanzar, MD Dr. Sanchez-Almanzar hails from Bogota, Colombia and graduated with his MD from Universidad de Los Andes in 2021. “I have always had a great interest in urology, and during my last year in medical school I had the opportunity to work in projects on congenital...