Dr. Chen’s group at Baylor College of Medicine (Houston, Texas) is broadly interested in genetics of the human visual system diseases.  Our current ongoing research projects fall within the following interactive areas: 1) Identify and functional validate mutations and genes associated with inherited human retinal diseases; 2) Using single cell multi-omics technology to generate the cell atlas of the human visual system and characterize diseases at the single cell resolution; 3) Understand the molecular mechanisms of the retinal diseases through characterizing animal disease models and retinal organoids; 4) Develop gene and small molecule therapeutics for retinal degeneration diseases.  With a combination of both experimental and computational approach, our group provides an excellent environment for interdisciplinary research focusing on genetics and genomics in the visual system.  People in our group has diverse backgrounds, such as genetics, medicine, engineering, computer, and statistics.  Many cutting-edge technologies are utilized in our research, such as the next generation sequencing, single cell multi-omics, and deep learning, in combination with cell culture, retinal organoid, and mice and non-human primate models, offering excellent opportunities in cross training to further expand your skills.  We currently have multiple postdoc fellow positions.  Past experiences in the visual system (either in the anterior or the posterior segment) or computational biology is a plus. If interested, please contact rui chen at ruichen@bcm.edu.

You can also contact postdoc in the Chen lab, salma.ferdous@bcm.edu if you have any questions.