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Advancing a new regulatory pathway for conduct of osteoporosis clinical trials
Investigating bone mineral density (BMD) as a surrogate endpoint for fractures in future trials of osteoporotic treatments.
Musculoskeletal health in aging, osteoporosis and diabetes
Investigating the mechanisms underlying age-related changes in bone and muscle, as well as investigating the effects of diabetes on musculoskeletal health.
Advanced imaging techniques for assessing skeletal fragility
Establishing methods for using photon-counting computed tomography (PCCT) evaluation of bone density and microstructure
Musculoskeletal health in Indigenous populations
Studying an Indigenous forager-horticulturalist population to provides unique insights into skeletal aging in the absence of many modern risk factors.
Stress fractures in military recruits
Investigating why some recruits are more vulnerable to stress fractures during basic training
Musculoskeletal health in disuse and spaceflight
Examining the effects of spaceflight and disuse on the musculoskeletal system in both humans and rodents, including studying spaceflight effects on muscle, bone, and risk of fracture