Project Title: Neurobiology of REM Sleep
Project Contact: Dr. Vetrivelan Ramalingam (vramalin@bidmc.harvard.edu)
Research Type: Basic Science and Translational Research
Status: Flexible (full-time or part-time options available)
Work Modality: In-Person
Academic Level: Undergraduate, Graduate, Medical Student
Pay: Unpaid
Project Description: Rapid eye movement (REM) sleep is a distinct sleep state during which vivid dreams occur. This stage of sleep plays a critical role in emotional processing and several cognitive functions. Several neuropsychiatric disorders, including major depression, bipolar disorder, and post-traumatic stress disorder, are associated with severe dysregulation of REM sleep, but the underlying neural mechanisms are not well understood. The major goal of the project is to identify the neural circuit dysfunction responsible for REM sleep abnormalities in such disorders. The student who works on this project will be able to learn and apply advanced conditional genetic tools (e.g., optogenetics, chemo genetics, photometry) and behavioral techniques in animal models to study this complex problem.
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Project Title: Using Non-invasive Brain Stimulation to Treat Word Finding Difficulty in Chronic Traumatic Brain Injury
Project Contact: Hsueh-Sheng Chiang (hchiang3@bidmc.harvard.edu)
Research Type: Clinical Research
Status: Flexible (full-time or part-time options available)
Work Modality: In-Person
Academic Level: High School- 18+, College Undergraduate Student, Undergraduate Medical Student
Pay: Unpaid
Project Description: The purpose of this study is to learn more about how brain stimulation affects word finding problems in people who have a traumatic brain injury (TBI). The type of brain stimulation used is called transcranial direct current stimulation (tDCS). tDCS delivers low levels of electric current to the brain and high definition tDCS (HD-tDCS) delivers the current with multiple electrodes on the scalp. This current is delivered with HD-tDCS to parts of the brain that may help with remembering things. The investigators hope that this can help to improve word finding and memory problems in people with TBI.