Participating BIDMC Mentors (continuously updated)

Mentor: Dr. Stephen Juraschek, MD, PhD

Opportunity Title: Hypertension among Older Adults

Opportunity Type: Clinical Research

Opportunity Description: Hypertension affects 85% of older adults. Many have blood pressure that differ at home from clinic. Our AHA-certified hypertension clinic is one of the only hypertension centers of excellence in the country that performs 24-hour ambulatory blood pressure monitoring. We are conducting a number of innovative quality improvement projects focused on improved blood pressure measurement in the clinic setting, including home blood pressure monitoring and automated office-based blood pressure monitoring. We are also creating a registry of ambulatory blood pressure measurements, which will be used to characterize blood pressure variability at home in a wide range of general medicine patients, yielding novel and previously uncharacterized insights on blood pressure regulation in a number of understudied populations. This experience provides students opportunities to: (1) Learn the process of registry creation in the context of clinical practice for rigorous quality improvement projects (2) Participate in publications related to blood pressure measurement and hypertension diagnosis at home and in clinic (3) Collaborate with clinics throughout Harvard (and eventually nationally outside Harvard) to grow the registry (4) Work with an innovative team to improve the technologic implementation of blue-tooth enabled home blood pressure monitors in clinical practice

Mentor: Dr. Stephen Juraschek, MD, PhD

Opportunity Title: DASH Groceries for Urban Food Deserts

Opportunity Type: Clinical Research

Opportunity Description: High blood pressure affects nearly 50% of adults in the US. Access to healthful foods is a critical barrier to preventive efforts to prevent hypertension and cardiovascular disease. We are conducting two randomized clinical trials to deliver groceries to Black adults living in Boston food deserts. We will recruit participants through 3 Beth Israel Clinics. Our primary outcome will be blood pressure. This experience provides students opportunities to: (1) Learn about clinical trial implementation and would emerge with knowledge on how to conduct trials; (2) Participate in the publications related nutrition, health access, and blood pressure using data sets including NHANES as well as prior clinical trials. (3) Participate in planning novel nutrition interventions involving HUD and other government subsidized meal programs (4) Network with institutions throughout the U.S. as part of an American Heart Association Strategic Network focused on health equity

Mentor: Dr. Stephen Juraschek, MD, PhD

Opportunity Title: Equitable Recruitment of Underrepresented Groups into Cardiovascular Trials

Opportunity Type: Clinical Research

Opportunity Description: We are funded by the American Heart Association as part of a Strategically Focused Research Network (SFRN) focused on improving diversity and representation in clinical trials. We are working with a national team of investigators from University of Vermont and Johns Hopkins University to study strategies for improving outreach and enrollment of underrepresented communities. Our team is multidisciplinary and includes cardiologists, general internists, ethicists, computer scientists, and nursing. Students have the opportunity to participate in the design of novel recruitment experiments as well as lead research for presentation at conferences and publication. Through this opportunity students will gain experience in clinical trials, clinical trial recruitment, primary data collection, and experience in scientific data interpretation and communication. Moreover, there are amble opportunities for expanding professional networks through working in a national network. We have an excellent track record of mentorship with students and would be delighted to have you join our team!

Mentor: Dr. Kenneth Mukamal, MD

Opportunity Title: Population Health Research on Cardiovascular Disease, Diabetes, and Dementia in Older Adults

Opportunity Type: Clinical Research

Opportunity Description: The Cardiovascular Health Study (CHS) is an ongoing cohort study that began in 1990 and has continued to follow 5,888 older adults through the end of their lives. Extensive information has been collected on a continual basis, including blood samples for genomics, proteomics, and metabolomics, environmental phenotyping, and collection of all hospitalizations and Medicare claims. Analytic support is available, so that students can (but need not) conduct their own biostatistical analyses.

Mentor: Mingyu Zhang, PhD

Opportunity Title: Metal Mixtures and Women's Mid-life Cardiometabolic Health in Project Viva

Opportunity Type: Clinical Research

Opportunity Description: The goal of this project is to investigate the impact of exposure to a "mixture" of heavy metals and trace elements during pregnancy and at 3 years postpartum on women’s mid-life cardiometabolic health. Additionally, it examines how adherence to healthy lifestyle behaviors (i.e., healthy diet, physical activity, avoiding smoking, and adequate sleep) may mitigate the adverse effects of heavy metals. Participants are from Project Viva, a prospective pregnancy cohort initiated in 1999-2002 to study how environmental and lifestyle factors affect the long-term health of women and their children (https://www.projectviva.org/). Students will have the opportunity to lead research projects, conduct data management and analysis, present at scientific conferences, and author peer-reviewed manuscripts. This research opportunity is based at Beth Israel Deaconess Medical Center with close collaboration with the Harvard Pilgrim Health Care Institute.

Mentor: Mingyu Zhang, PhD

Opportunity Title: Pregnancy Metal Exposures and Diabetes Risks Across the Reproductive Lifespan of Black and Hispanic Women

Opportunity Type: Clinical Research

Opportunity Description: The goal of this project is to understand the impacts of pregnancy exposure to a mixture of toxic metals (Pb, Hg, Cd) and trace elements (Mn, Se) on diabetes risks across the reproductive lifespan of Black and Hispanic women, from gestational diabetes (GDM) during pregnancy to type 2 diabetes (T2D) in mid-life. The project also aims to uncover how metals could be an underrecognized source of racial and ethnic disparities in the progression from GDM to incident T2D. Participants are from the Boston Birth Cohort, a large, long-standing (over 20 years of follow-up), prospective U.S. cohort that comprises predominantly urban, low-income, and minority women. Students will have the opportunity to lead research projects, conduct data management and analysis, present at scientific conferences, and author peer-reviewed manuscripts. This research opportunity is based at Beth Israel Deaconess Medical Center with close collaboration with the Center on the Early Life Origins of Disease at Johns Hopkins University.

Mentor: Dr. Chenxi Qiu, PhD

Opportunity Title: Responsible/Interpretable AI for Science

Opportunity Type: Basic Science Research

Opportunity Description: We are building AI systems that combine fleets of specialized agents with carefully engineered scientific harnesses to accelerate biological discovery. These systems autonomously interrogate large functional-genomic datasets, develop and test predictive models, and iteratively refine scientific hypotheses under human oversight. One example is our recent participation in the Virtual Cell Challenge, where we used a multi-agent system to approach complex biological questions and explore the potential of AI to drive scientific discovery. Our broader goal is to develop AI that functions as a rigorous scientific collaborator, to help uncover biological rules and generate discoveries that conventional workflows may miss.

Mentor: Sizun Jiang, PhD

Opportunity Title: Spatial-omics and Systems Immunology: Finding clinical insights from tissues

Opportunity Type: Translational Research

Opportunity Description: The Jiang lab (https://sizunjianglab.com/) develops cutting edge spatial technologies across experimental and computational platforms towards clinically impactful and deployable assays. We broadly study a spectrum of diseases from cancer, autoimmunity to infectious diseases. Our recent work include work into spatial multi-omics technologies (Immunity 2022, Nature Communications 2023, 2025, Cancer Discovery in revision), machine learning approaches (Nature Communications 2024, Nature Immunology 2025, Nature in revision), clinically deployable technologies (Nature Methods accepted, Nature Methods in revision), and their applications to various diseases such as Chronic Rhinosinusitis (Immunity 2025), Hodgkin's Lymphoma (Immunity in revision), and others. Ongoing work including AI foundation models and agentic aspects, spatial-omics and their applications in health and diseases, amongst others. We look forward to working together!

Name:

Name: Tina Porter, MD

Project Name: Prospective Evaluation of Disease Flare in Hidradentis Suppurativa

Research Type: Translational Research

Research Description: The student will be supporting an HS flares research project, including collecting data, performing data analysis, etc.

Name: William Lewis, MD

Project Name: Computational Photography and Image Processing in Dermatology

Research Type: 

Research Description: Students will have the opportunity to work with me on project(s) related to image processing and software development for dermatology, especially related to visualizing erythema in patients with skin of color and inflammatory disease. Students will have the opportunity to work on image processing algorithm development, validation, and implementation. Through this project, they will gain experience with the optical properties of skin and light-tissue interaction, image capture and processing, and dermatologic disease. Motivated students, especially those with previous experience in software development, may be able to contribute to the creation of a mobile phone application. It is expected that the student's work will lead to the generation of a first-author publication in a dermatology journal.

Name: Sarah Berry, MD

Project Title: Preventing Injury in Skilled Nursing Facilities through Medication Optimization (PRISM): a randomized cluster cross-over trial in post-acute patients with fracture

Project Type: Clinical Research

Project Description: Presently I am the PI of a large randomized trial in 42 skilled nursing facilities across 13 states to compare the effectiveness of a Deprescribing Care model, a Bone Health Model, and a Combined Injury Prevention Model on rates of injurious falls in patients recovering from a fracture. While the primary outcomes will not be available for sometime, our group has considerable data (by Spring 2026 anticipate more than 2000 patients enrolled) on medications, what matters most, perceptions of deprescribing and osteoporosis treatment. Students could examine variations in facility or regional prescribing practices, uptake of the intervention, or to explore the relationship between the matters most question and deprescribing. Students would have the opportunity to participate in weekly team meetings with a large multidisciplinary team. Ideally the student would be interested in leading a first author publication with support from the team.

Name: 

Name: Christopher Ogilvy, MD

Project Name: Outcomes for surgical and endovascular treatment of unruptured intracranial aneurysms

Research Type: Clinical Research

Project Description: New perspective on outcomes for aneurysm surgery and endovascular treatment of unruptured aneurysms looking at combined modality management with cognitive and functional outcomes

Mentor: Christos Mantzoros, MD

Opportunity Title: Harnessing multi-omics and machine-learning for cardiometabolic risk prediction in MASLD/MASH

Opportunity Type: Translational Research

Opportunity Description: Our Translational Endocrinology Research Laboratory at Beth Israel Deaconess Medical Center, Harvard Medical School, focuses on understanding the pathophysiology, diagnostic, and prognostic mechanisms underlying metabolic diseases. Our work bridges basic and clinical science through a wide portfolio of translational and clinical studies. The goal of this project is to investigate the multi-omics signatures of cardiometabolic outcomes in biopsy-proven adults with metabolic dysfunction-associated steatotic liver disease (MASLD) or metabolic dysfunction-associated steatohepatitis (MASH). Additionally, we intend to develop machine-learning models to create more accurate risk prediction models in this population. Scholars Students will have the opportunity to: a) Learn techniques in data management, biomarker analysis, and statistical software (R, Python, SPSS). b) Contribute to manuscript preparation, figure design, and literature review under mentorship from postdoctoral fellows and faculty. c) Attend weekly lab meetings.

Mentor: Christos Mantzoros, MD

Opportunity Title: Translational Endocrinology Research Laboratory (Mantzoros Lab, BIDMC / Harvard Medical School)

Opportunity Type: Translational Research

Opportunity Description: Our Translational Endocrinology Research Laboratory at Beth Israel Deaconess Medical Center, Harvard Medical School, focuses on understanding the pathophysiology, diagnostic, and prognostic mechanisms underlying metabolic diseases. Our work bridges basic and clinical science through a wide portfolio of translational and clinical studies.Research Areas 1. Metabolic Dysfunction–Associated Steatohepatitis (MASH)/Metabolic Dysfunction-Associated Steatotic Liver Disease MASLD)
We conduct observational and interventional studies to identify molecular, hormonal, and clinical predictors of disease progression. Our current work focuses on validation of non-invasive diagnostic and prognostic biomarkers for MASH/MASLD. 2. Clinical Trials in Cardiometabolic Medicine:
We are currently participating in a multicenter clinical trial evaluating the cardiometabolic effects of an investigational compound (novel weight loss medication). 3. Hormonal and Omics Research on GLP-1 effects:
Ongoing metabolomic, proteomic, and hormonal studies are being performed to uncover pathways regulating body composition changes (lean mass, fat mass, bone mass). We integrate clinical data, laboratory assays (ELISA) and multi-omic analyses to translate molecular findings into clinically meaningful insights. Opportunities for Scholars Students will have the opportunity to: -Learn techniques in data management, biomarker analysis, and statistical software (SPSS, GraphPad, R). -Contribute to manuscript preparation, figure design, and literature review under mentorship from postdoctoral fellows and faculty. -Attend weekly lab meetings. This experience offers an outstanding opportunity for motivated students to explore the fundamentals of research and engage in hands-on laboratory work.

Name: Yarden Fraiman, MD

Opportunity Title: Understanding Macro-level Drivers of Inequity for Infants and Children

Opportunity Type: Translational Research

Opportunity Description: Dr. Fraiman's lab is a health services health equity research lab focused on measuring, understanding, and addressing the modifiable macro-level drivers--structural and institutional racism--that drive inequity for newborns and across their life-course within and outside of the healthcare system. Research opportunities include large data epidemiologic research, chart review and data extraction, qualitative research, implementation science, and clinical equity-focused quality improvement. Students will receive hands-on mentorship from Dr. Fraiman and members of the research team. Students will have a scholarly project to present at the completion of the mentored experience and will be included as authors, including as first authors, when projects are completed.